Case Report
 
Emphysematous pyelonephritis in a non-diabetic patient associated with nephrolithiasis: A rare case report
Sônia M. H. A. Araújo1, Mateus P. M. Feitosa1, Priscila D. Evangelista1, Sarah F. Sá1 Jarinne C. L. Nasserala1, Yuri Nóbrega1, Pedro Miguel A. Pinheiro1, Nicole Almeida de Alencar Araújo1 Elizabeth F. Daher1, Geraldo B. Silva Junior1
1School of Medicine, University of Fortaleza. Fortaleza, Ceará, Brazil; School of Medicine, Federal University of Ceará. Fortaleza, Ceará, Brazil.

doi:10.5348/ijcri-201525-CR-10486

Address correspondence to:
Sônia M. H. A. Araújo
Curso de Medicina. Universidade de Fortaleza. Av. Washington Soares
1321. CEP: 60811-905
Fortaleza, Ceará
Brazil

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How to cite this article
Araùjo SMHA, Feitosa MPM, Evangelista PD, Sá SF, Nasserala JCL, Nóbrega Y, Pinheiro PMA, Araùjo ADA, Daher EF, Silva Junior GB. Emphysematous pyelonephritis in a non-diabetic patient associated with nephrolithiasis: A rare case report. Int J Case Rep Images 2015;6(3):138–141.


Abstract
Introduction: Emphysematous pyelonephritis (EP) is an acute renal infection, potentially fatal, with high mortality, which is more frequent in women at fifth decade of life. Herein, we describe a case of EP successfully treated with surgery.
Case Report: A 50-year-old female was admitted with complaints of lumbar pain, irradiating to ipsilateral lower limb, associated with nausea and fever (38.9°C), with chills. Abdominal computed tomography (CT) scan showed amorphous echogenic image, with gaseous component, inside the right kidney, and pyelogram showing lithiasis in the right renal pelvis and filling defect. Urine culture was positive for Escherichia coli. Antibiotic therapy was initiated with piperacillin-tazobactam and opioids. On 15th day of hospital stay, she underwent a right nephrectomy. The histopathological analysis evidenced numerous sclerosed glomeruli, tubules with atrophy, inflammatory infiltrate in the interstitium. She was discharged with complete resolution of the infection, asymptomatic and with normal renal function.
Conclusion: Emphysematous pyelonephritis is a rare, atypical, and severe form of renal parenchyma infection. Early nephrectomy (<1 week) is associated with increased mortality in comparison to conservative treatment. In this case, the patient underwent an elective nephrectomy due to the chronicity of the disease, with successful recovery.

Keywords: Emphysematous pyelonephritis, Infection, Nephrolithiasis, Non-diabetic patient, Renal failure, Urinary infection


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Author Contributions
Sônia M. H. A. Araújo – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Mateus P. M. Feitosa – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Priscila D. Evangelista – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sarah F. Sá – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jarinne C. L. Nasserala – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Yuri Nóbrega – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Pedro Miguel A. Pinheiro – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Nicole Almeida de Alencar Araújo – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Elizabeth F. Daher – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Geraldo B. Silva Junior – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2015 Sônia M. H. A. Araújo et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.