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Case Report
 
Cystic hygroma of arm treated with OK-432: A case report
Chin Aun Low1, Foead Agus Iwan2
1MBBS, Medical Officer, Department of Orthopaedic Surgery, Hospital Tuanku Ampuan Najihah, Kuala Pilah, Malaysia.
2MS Orth, Specialist, Department of Orthopaedic Surgery, Hospital Tuanku Ampuan Najihah, Kuala Pilah, Malaysia.

doi:10.5348/ijcri-2014143-CR-10454

Address correspondence to:
Chin Aun Low
Jalan Melang, 72000 Kuala Pilah
Negeri Sembilan
Malaysia, Postal code: 72000
Phone: +6012-2303500
Email: robinlca@gmail.com

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How to cite this article
Low CA, Iwan FA. Cystic hygroma of arm treated with OK-432: A case report. Int J Case Rep Images 2014;5(12):831–834.


Abstract
Introduction: Cystic hygroma is a type of lymphangioma and is located most frequently in the head and neck region, followed by axilla, superior mediastinum, and mesentery and retroperitoneal. Its occurrence in upper extremity is rarely reported in literature.
Case Report: We report a newborn baby with Down's syndrome presented with cystic hygroma in his left arm and forearm. Patient was treated with OK-432 for the swelling of the left arm. However, patient presented at five months of age with severe sepsis secondary to gangrene of left arm and concomitant meningitis which subsequently led to his death.
Conclusion: Picibanil aka OK-432 has been increasingly used for the last two decades for the treatment of cystic hygroma with much success. However, few literatures report of serious morbidity with its use. More case controlled studies should be carried out to further understand the side effects of sclerosant therapy, as it has the potential to be ideal treatment for cystic hygroma in the future.

Keywords: Cystic hygroma, Lymphangioma, Picibanil, Neonatal gangrene


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Author Contributions
Chin Aun Low – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Foead Agus Iwan – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2014 Chin Aun Low et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.