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Case Report
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| Nigrospora sphaerica causing corneal ulcer in an immunocompetent woman: A case report | ||||||
| Ananya TS1, Anupma Jyoti Kindo2, Anandhalakshmi Subramanian3, Kalpana Suresh4 | ||||||
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1MBBS, MD Postgraduate, Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Chennai, Tamil Nadu, India.
2MD, Professor, Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Chennai, Tamil Nadu, India. 3MBBS, MS Postgraduate, Department of Ophthalmology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Chennai, Tamil Nadu, India. 4MS, Professor, Department of Ophthalmology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Chennai, Tamil Nadu, India. | ||||||
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| How to cite this article |
| Ananya TS, Kindo AJ, Subramanian A, Suresh K. Nigrospora sphaerica causing corneal ulcer in an immunocompetent woman: A case report. Int J Case Rep Images 2014;5(10):675–679. |
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Abstract
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Introduction:
Corneal ulcers secondary to trauma can often pose a clinical challenge. The causative pathogen is at times an unusual and resistant microorganism which may not be identified by conventional laboratory techniques.
Case Report: A 45-year-old immunocompetent woman with a history of injury of right eye with a cow's tail was diagnosed to have fungal corneal ulcer. Sporulation of the isolate occurred after prolonged incubation and the pathogen was found to be Nigrospora sphaerica. The number of cases of true infection caused by this fungus amount to only five in available literature. The patient did not improve with medical management using natamycin and ketoconazole and underwent voriconazole therapy. Conclusion: Delayed sporulation of pathogenic fungal isolates may necessitate prolonged incubation and use of multiple sporulation techniques for the purpose of speciation. Uncommon fungi also need to be kept in mind when dealing with an unresponsive/worsening clinical situation. | |
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Keywords:
Fungal keratitis, Nigrospora sphaerica, Black fungi, Voriconazole
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Author Contributions
Ananya TS – Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Anupma Jyoti Kindo – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Anandhalakshmi Subramanian – Acquisition of data, Critical revision of the article, Final approval of the version to be published Kalpana Suresh – Conception and design, Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2014 Ananya TS et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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About The Authors
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