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Case Report
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Cutaneous metastatic breast adenocarcinoma twenty years post-mastectomy: A lesson to learn | ||||||
Armand Asarian1, Olubunmi Esan2, Philip Xiao3, Segun Adeoye4 | ||||||
1MD, Consultant Surgeon, Program Director, General Surgery Residency Program, Department of Surgery, The Brooklyn Hospital Center (TBHC), Brooklyn, NY, USA.
2MD, General Surgery Resident, Department of Surgery, The Brooklyn Hospital Center, Brooklyn, NY, USA. 3MD, Consultant Pathologist, Department of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, USA. 4MD, MS, Attending Physician, Hospital Unit, University of Pittsburgh Medical Center (UPMC), Horizon, Greenville, PA, USA. Former Resident, The Brooklyn Hospital Center. | ||||||
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How to cite this article |
Asarian A, Esan O, Xiao P, Adeoye S. Cutaneous metastatic breast adenocarcinoma twenty years post-mastectomy: A lesson to learn. Int J Case Rep Images 2014;5(9):614–618. |
Abstract
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Introduction:
Cutaneous metastasis complicating solid organ malignancy is a common clinical entity, and the primary is often metastatic breast cancer. Skin metastasis from breast cancer occurs in about 25% of breast cancer patients.
Case Report: We present a case report of a patient with a history of modified left radical mastectomy and chemo-therapy for breast cancer twenty years earlier, who presented for surgical evaluation of multiple painful skin lesions. Initial punch biopsy of skin lesions reported negative for malignancy. Surgical biopsy provided tissue which demonstrated a rare histopathological morphology for cutaneous metastatic breast adenocarcinoma. Conclusion: This report makes the case for considering surgical biopsy when conventional biopsy reports negative for malignancy, especially in the setting of remote or recent cancer history. It also advises prolonged relapse surveillance, well beyond the current protocol, as well as development of prognostic markers for identifying patients at risk of long disease latency after primary treatment. | |
Keywords:
Cutaneous metastasis, Metastatic breast cancer, Breast cancer with cutaneous metastasis, Cutaneous metastatic breast adenocarcinoma
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Author Contributions
Armand Asarian – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Olubunmi Esan – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Philip Xiao – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Segun Adeoye – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
Guarantor of submission
The corresponding author is the guarantor of submission. |
Source of support
None |
Conflict of interest
Authors declare no conflict of interest. |
Copyright
© 2014 Armand Asarian et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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