  |
|
 |
|
Case Series
| ||||||
| Sarcoma botryoides a management dilemma: A review of two cases | ||||||
| Aliyu Labaran Dayyabu1, Adogu IO2, Makama BS3 | ||||||
|
1Obstetrics & Gynaecology Department ATBUTH Bauchi, Nigeria.
2Department of Pathology ATBUTH Bauchi. 3Department of Surgery ATBUTH Bauchi. | ||||||
| ||||||
|
[HTML Full Text]
[PDF Full Text]
[Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar] 
|
| How to cite this article |
| Dayyabu AL, Adogu IO, Makama BS. Sarcoma botryoides a management dilemma: A review of two cases. Int J Case Rep Images 2014;5(7):482–487. |
|
Abstract
|
|
Introduction:
Sarcoma botryoides is a rare and rapidly growing tumor affecting primarily the female genital tract of children. It presents as bleeding per vaginum or as a polypoid fleshy mass protruding through the vagina. Treatment is surgery combined with multidrug chemotherapy. In developing environment, one has to contend with late presentation, availability and affordability of cytotoxics and the surgical options available at advanced stage, their acceptability, their management postoperative and their impact on quality of life.
Case Series: The first case was a four-year-old child who presented with a rapidly growing mass protruding per vaginum, intermittent vaginal bleeding and difficulty in passing stool and urine. She had examination under anesthesia and biopsy. Histology confirmed sarcoma botryoides. Her parents opted for multidrug chemotherapy and was treated with a combination of cylophosphamide, vincritine and doxorubicin. She had six courses of the drugs with remarkable improvement in symptoms and the tumor regressed almost completely. Patient was subsequently lost to follow-up. The second case was a six-month-old child who presented with vaginal bleeding, vaginal growth and abdominal swelling. Histology confirmed sarcoma botryoides and the parents were counselled on management options which they declined and took the child home. The child was brought back with obstructive uropathy and septicemia. She had suprapubic cystostomy to relieve the obstruction. However, her condition deteriorated and she died a week after admission. Conclusion: Sarcoma botryoides is a rapidly growing malignancy, early presentation and prompt and aggressive surgery combine with multidrug chemotherapy may be the answer if outcome is to be improved. To ensure this in low resource countries free health care for children and all individuals with malignancies and chronic debilitating diseases should be provided. In addition education and poverty alleviation will further save the situation. | |
|
Keywords:
Sarcoma botryoides, Rhabdo- myosarcoma, Multidrug chemotherapy
| |
|
[HTML Full Text]
[PDF Full Text]
|
|
Author Contributions:
Aliyu Labaran Dayyabu – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Adogu IO – Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published Makama BS – Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published |
|
Guarantor of submission
The corresponding author is the guarantor of submission. |
|
Source of support
None |
|
Conflict of interest
Authors declare no conflict of interest. |
|
Copyright
© 2014 Aliyu Labaran Dayyabu et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
|
|