Case Report
 
Short-lived delirium caused by single-shot corticosteroids
Johannes Prottengeier1, Stefan Leucht2, Torsten Birkholz3
1MD,Resident, Department of Anesthesia, University Hospital, Erlangen, Germany.
2MD, Professor of Psychiatry, Deputy Head, Department of Psychiatry, Technical University of Munich, Germany.
3MD, Assistant Professor of Anesthesiology, Consultant, Department of Anesthesia, University Hospital, Erlangen, Germany.

doi: 10.5348/ijcri-201455-CR-10366

Address correspondence to:
Johannes Joachim Prottengeier
MD, Department of Anesthesia
Erlangen University Hospital, Krankenhausstraße 12
D-91054 Erlangen
Germany
Phone: +49-9131-85-42332
Fax: +49-9131-85-36147
Email: johannes.prottengeier@kfa.imed.uni-erlangen.de

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How to cite this article
Prottengeier J, Leucht S, Birkholz T. Short-lived delirium caused by single-shot corticosteroids. International Journal of Case Reports and Images 2014;5(4):270–272.


Abstract
Introduction: Corticosteroids have many indications in medicine. Side effects are not uncommon, but psychiatric disorders in response to a single dose treatment are very rare.
Case Report: We report of a previously mentally healthy 43-year-old female who received a single dose of 4 mg intramuscular dexamethasone and subsequently developed a short-lived delirium within hours of administration.
Conclusion: Steroid delirium and psychosis are well known in literature, but reports on such an immediate adverse reaction are rare. The underlying biochemical mechanisms are unknown, but prognosis upon discontinuation of steroid intake is generally favorable.

Keywords: Steroids, Delirium, Single-shot corticosteroids, Adverse drug reaction


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Author Contributions
Johannes Prottengeier – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Stefan Leucht – Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
TorstenBirkholz – Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© Johannes Prottengeier et al. 2014; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)