Case Report
 
Wilkie's syndrome: A rare cause of vomiting and weight loss
Ali Coşkun1, Deniz Uçar1, Erdem Bariş Carti1, Erkan Oymaci1, Mehmet Yildirim1, Nazif Erkan1
1Izmir Bozyaka Training and Research Hospital, Department of General Surgery.

doi:10.5348/ijcri-2014-02-461-CR-13

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Email: dralicoskun@hotmail.com

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How to cite this article
Coşkun A, Uçar D, Carti EB, Oymaci E, Yildirim M, Erkan N. Wilkie's syndrome: A rare cause of vomiting and weight loss. International Journal of Case Reports and Images 2013;5(2):150–154.


Abstract
Introduction: Superior mesenteric artery (SMA) syndrome, also known as Wilkie's syndrome, is extremely rare and is characterized by postprandial epigastric pain, nausea, vomiting and loss of appetite, with subsequent weight loss, which aggravates the condition of the patients. The syndrome is caused by compression of the third part of the duodenum in the angle between the aorta and the superior mesenteric artery. Herein, we presented a patient with Wilkie's syndrome and discussed the diagnostic difficulties and surgical treatment options.
Case Report: We report a case of a 13-year-old female who was diagnosed with SMA syndrome. There was no history of recent trauma, surgery, prolonged immobilisation or neurological illness. Her weight loss was gradual. The patient was initially diagnosed as anorexia nervosa due to her symptoms of vomiting and anorexia without any clinical cause, but later on, she underwent computed tomography scan and was diagnosed with SMA syndrome. Her SMA syndrome, resolved after successful nonoperative management based on accepted guidelines for nutritional therapy, thus avoiding the need for operation. One year follow-up was uneventful.
Conclusion: Superior mesenteric artery syndrome is a rare cause of intestinal obstruction and its first-line treatment is usually conservative with jejunal or parenteral nutrition for restoration of the aortomesenteric fatty tissue. If conservative management fails, surgical options , open or laparoscopic duodenojejunostomy or duodenal mobilization. Its recognition is important because early diagnosis of a partial obstruction may allow for medical rather than surgical intervention, as exemplified by our case.

Keywords: Superior mesenteric artery (SMA) syndrome, Wilkie's syndrome, Weight loss, Vomiting, Enteral feeding


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Author Contributions
Ali Coşkun – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Deniz Uçar – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Erdem Bariş Carti – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Erkan Oymaci – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mehmet Yildirim – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Nazif Erkan – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© Ali Coşkun et al. 2014; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)



About The Authors

Ali Coşkun is resident at Department of Surgery, Izmir Training and Research Hospital. His research interests include upper gastrointestinal and endocrine surgery. He has published 25 research papers in academic journals.



Deniz Uçar is resident at Department of Surgery and Burn Center, Izmir Training and Research Hospital. His research interests include burn, colon and rectum surgery. He has published 8 research papers in academic journals.



Erdem Bariş Carti is resident at Department of Surgery, Izmir Training and Research Hospital. His research interests include hepatopancreatobiliary and breast. He has published 10 research papers in academic journals.



Erkan Oymaci is resident at Department of Surgery, Izmir Training and Research Hospital. His research interests include gastrointestinal surgery and endoscopy. He has published 8 research papers in academic journals.



Mehmet Yildirim is resident at Department of Surgery, Izmir Training and Research Hospital. His research interests include upper gastrointestinal surgery. He has published 30 research papers in academic journals.



Nazif Erkan is resident at Department of Surgery, Izmir Training and Research Hospital. His research interests include gastric and colorectal surgery. He has published more than 50 research papers in academic journals.