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Case Report
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| Tophi gout around the knee joint: An unusual presentation with a soft tissue mass | ||||||
| Feyza Unlu Ozkan1, Kerem Bilsel2, Ismail Turkmen3, Mehmet Erdil2, Salih Soylemez3, Korhan Ozkan3 | ||||||
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1MD, Fatih Sultan Mehmet Education and Research Hospital; Physical Medicine and Rehabilitation Department; Istanbul, Turkey.
2MD, Bezmialem Vakif University; Orthopaedic and Traumatology Department; Istanbul, Turkey. 3MD, Istanbul Medeniyet University Goztepe Education and Research Hospital; Orthopedics and Traumatology Department; Istanbul, Turkey. | ||||||
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| How to cite this article: |
| Ozkan FU, Bilsel K, Turkmen I, Erdil M, Soylemez S, Ozkan K. Tophi gout around the knee joint: An unusual presentation with a soft tissue mass. International Journal of Case Reports and Images 2013;4(11):593–596. |
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Abstract
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Introduction:
Gout is the most common inflammatory arthropathy. It has been reported to affect 2.13% of population in the United States. In this report, we presented an uncommon case of tophaceous gout of the knee presenting as a soft tissue mass.
Case Report: A 57-year-old male patient with knee pain and localized progressive swelling increasing in time on the medial side of the proximal tibia was seen in our clinic. He did not have any rheumatologic disease known previously except gout arthritis. Excisional biopsy was performed by preserving medial collateral ligament and histopathologic investigations were done next. A tophaceous gouty deposit was identified by low-power photomicrograph. A bluish amorphous material was seen surrounded by bundles of dense collagenized tissue and chronic inflammatory cells. Surrounding the amorphous crystalline deposit is a thin layer of mononuclear and giant cells. Photomicrograph of another section has been stained by de Galantha’s method for demonstration of monosodium urate crystals. Conclusion: Especially in patients with extra-articular or subcutaneus mass, tophaceous gout must be considered as differential diagnosis. | |
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Keywords:
Tophi gout, de Galantha’s method, Tophaceous gout, Gout arthritis
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Author Contributions
Feyza Unlu Ozkan – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Kerem Bilsel – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Ismail Turkmen – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Mehmet Erdil – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Salih Soylemez – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Korhan Ozkan – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Feyza Unlu Ozkan et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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