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Case Report
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| Solitary plasmacytoma of clavicle: A case report | ||||||
| Aruj Dhyani1, Abhash Shankar1, Arunima Gupta1, Rupesh Kumar2, Koushik Chatterjee3, Anup Majumdar4 | ||||||
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1MBBS, Junior resident, Department of Radiotherapy, IPGME&R/SSKM Hospital, Kolkata, West Bengal, India.
2MBBS, MS, MCh, Mch trainee, Department of CTVS, IPGME&R/SSKM Hospital, Kolkata, West Bengal, India. 3MBBS, MD, Assistant professor, Department of Radiotherapy, IPGME&R/SSKM Hospital, Kolkata, West Bengal, India. 4MBBS, MD, Professor & HOD, Department of Radiotherapy, IPGME&R/SSKM Hospital, Kolkata, West Bengal, India. | ||||||
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| How to cite this article: |
| Dhyani A, Shankar A, Gupta A, Kumar R, Chatterjee K, Majumdar A. Solitary plasmacytoma of clavicle: A case report. International Journal of Case Reports and Images 2013;4(8):440–443. |
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Abstract
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Introduction:
Plasmacytoma is a localized collection of malignant plasma cells. The disease can be divided into solitary plasmacytoma of the bone (SPB) and extramedullary plasmacytoma (EMP), both of which are distinct entities. An EMP, the rarer of the two, has soft tissue infiltration by clonal plasma cells without any occult or systemic myeloma. Whereas, SPB has a solitary lytic bone lesion with infiltration of monoclonal plasma cells, with absence of the same on a random marrow sampling or any evidence of systemic myeloma. Though SPB may involve any bone in the body but involvement of medial end of clavicle, though reported, is extremely rare.
Case Report: Herein, we report a case of a 65-year-old farmer presented with pain and swelling of the medial end of the left clavicle, which was postoperatively diagnosed to be a solitary plasmacytoma by virtue of histopathology and IHC, with no other evidence of osteopenic lesions on radiographs, a negative bone scan, absence of marrow involvement by monoclonal plasma cells, presence of M-band on serum protien electrophoresis, in the IgG region and no evidence of anemia, hypercalcemia, hyperuricemia, hypercreatininemia, nephropathy, respiratory and urinary tract infections that can suggest the presence of any systemic myeloma. Conclusion: The case of solitary plasmacytoma of the clavicle reported here is a very rare as a disease entity, and rarest because of the site of involvement. The patient was treated with surgery and radiotherapy and had excellent disease control. | |
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Keywords:
Solitary plasmacytoma bone (SPB), Multiple myeloma, Clavicle, Extramedullary plasmacytoma
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Author Contributions
Aruj Dhyani – Conception and design, Drafting the article, Final approval of the version to be published Abhash Shankar – Analysis and interpretation of data, Drafting the article, Final approval of the version to be published Arunima Gupta – Acquisition of data, Critical revision of the article, Final approval of the version to be published Rupesh Kumar – Acquisition of data, Critical revision of the article, Final approval of the version to be published Koushik Chatterjee – Conception and design, Critical revision of the article, Final approval of the version to be published Anup Majumdar – Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Aruj Dhyani et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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