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Case Report
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| A peripheral neuropathy with unusual progression in Wegener's granulomatosis | ||||||
| Nayef Mohammed Kazzaz1, Scott Louis Massien2 | ||||||
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1MD, PGY-2 Resident, Internal Medicine Department, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland.
2MD, Scott Massien MD, ABIM, Clinical Instructor, Internal Medicine, University Hospitals Ahuja Medical Center, Kathy Risman Pavilion, 1000 auburn drive suite 110, Beachwood. | ||||||
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| How to cite this article: |
| Kazzaz N M, Massien S L. A peripheral neuropathy with unusual progression in Wegener's granulomatosis. International Journal of Case Reports and Images 2013;4(7):341–344. |
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Abstract
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Introduction:
We present a case of Wegener's granulomatosis with unique sequence of progression into a rare presentation of peripheral neuropathy; previously there has been one similar case. However, instead of the two years lag after sinusitis development our case manifested with peripheral neuropathy in a quick fashion. Also we have observed a chronological sequence of progression from infectious process into Wegener's granulomatosis.
Case Report: We present a case of a 66-year-old Caucasian male previously healthy who presented initially with symptoms of sinusitis and pneumonia, which in a span of three months presented with peripheral neuropathy advancing to left foot drop. Conclusion: In Wegener's granulomatosis, the symptoms of most prominence might not necessarily be the classical presentation of upper or lower respiratory involvement but could be neurological and does not always follow the course of chronic involvement before advancing to severe neurological consequence such as foot drop. In addition, the hypothesis that infections could have contributory role in development or is a factor in Wegener's granulomatosis is observed here in the chronological sequence of events from pneumonia to manifestation of the disease and nonetheless the seroconversion of C-ANCA to positivity. | |
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Keywords:
Wegener's granulomatosis (WG), Granulomatosis with polyangitis, Small vessel vasculitis, Peripheral neuropathy
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Author Contributions
Nayef Mohammed Kazzaz – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Scott Louis Massien – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Nayef Mohammed Kazzaz et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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