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Case Series
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| Combination therapy with vitamin D3, progesterone, omega-3 fatty acids and glutamine reverses coma and improves clinical outcomes in patients with severe traumatic brain injuries: A case series | ||||||
| Leslie R Matthews1, Omar K Danner1, Y A Ahmed2, Diane M Dennis-Griggs1, Alexis Frederick1, Clarence Clark1, Ronald Moore1, Wilson DuMornay1, Ed W Childs1, Kenneth L Wilson1, | ||||||
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1Morehouse School of Medicine, Department of Surgery, 720 Westview Drive, SW, Atlanta, GA, USA.
2Department of Epidemiology, King Saud University, College of Pharmacy, Riyadh, Kingdom of Saudia of Arabia. | ||||||
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| How to cite this article: |
| Matthews LR, Danner OK, Ahmed YA, Dennis-Griggs DM, Frederick A, Clark C, Moore R, DuMornay W, Childs EW, Wilson KL. Combination therapy with vitamin d3, progesterone, omega 3-fatty acids and glutamine reverses coma and improves clinical outcomes in patients with severe traumatic brain injuries: A case series. International Journal of Case Reports and Images 2012;4(3):143–149. |
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Abstract
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Introduction:
Traumatic brain injury (TBI) is a major public health problem and a leading cause of death and disability in the United States. Management of patients with TBI has changed very little over the last 20 years.
Case Series: A case series of three patients with severe TBIs who were aggressively treated with vitamin D3, progesterone, omega 3-fatty acids, and enteral glutamine for six weeks, termed neuroceutical augmentation for traumatic brain injury (NATBI), with very favorable outcomes. Conclusion: A large clinical study trial using these four supplements (NATBI) together is warranted. | |
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Keywords:
Traumatic brain injury, Vitamin D3, Omega-3 fatty acids, Loveza, Progesterone, Cerebral edema, Glutamine
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Author Contributions:
Leslie R Matthews – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Omar K Danner – Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Y A Ahmed – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Diane M Dennis-Griggs – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Alexis Frederick – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Clarence Clark – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Ronald Moore – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Wilson DuMornay – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Ed W Childs – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Kenneth L Wilson – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Leslie R Matthews et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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