  |
|
 |
|
Case Report
| ||||||
| Reversible myeloneuropathy and pancytopenia related to copper deficiency from gastric bypass surgery: A case report | ||||||
| Laide Bello1, Joseph Fiore2 | ||||||
|
1Department of Medicine, Steward Carney Hospital, TUFTS University School of Medicine, Boston, MA, 2100 Dorchester Avenue, Boston, Massachusetts, USA.
2Division of Gastroenterology, Seton Medical Office Building, Steward Carney Hospital, TUFTS University School of Medicine, Boston, MA 02124, 2110 Dorchester Avenue, Boston, Massachusetts, USA. | ||||||
| ||||||
|
[HTML Full Text]
[PDF Full Text]
[Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar] 
|
| How to cite this article: |
| Bello L, Fiore J. Reversible myeloneuropathy and pancytopenia related to copper deficiency from gastric bypass surgery: A case report. International Journal of Case Reports and Images 2013;3(1):24–27. |
|
Abstract
|
|
Introduction:
Weight loss surgery has become an increasingly popular means of combating the obesity epidemic in modern society but like any procedure, it does not shy away from immediate and long-term complications. Copper deficiency has occasionally been reported to occur many years afterwards but with an increased incidence of bariatric procedures and reduced awareness, the effects of this deficiency could now appear to favor an earlier onset.
Case Report: We report a case of a 56-year-old Caucasian female with a history of gastric bypass surgery five year ago; with an unsteady gait, weakness, decreased visual acuity, tingling with numbness in her hands and pancytopenia for the last month. She was treated for copper deficiency. Conclusion: Effects of copper deficiency have been shown to cause a wide array of abnormalities related to inactivation of enzymes such as cytochrome c oxidase, superoxide dismutase, dopamine beta hydroxylase and metallothionein. This can lead to reduced nerve transmission within the central nervous system causing motor and sensory polymyeloneuropathy and an overall reduction of energy required for blood cell formation. With early surveillance, such anomalies can be detected and potentially reverse the effects of this micronutrient deficiency. | |
|
Keywords:
Myeloneuropathy, Hemoglobinopathy, Micronutrient deficiency
| |
|
[HTML Full Text]
[PDF Full Text]
|
|
Author Contributions
Laide Bello – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, revising it critically for important intellectual content, Final approval of the version to be published Joseph Fiore – Substantial contributions to conception and design, Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
|
Guarantor of submission
The corresponding author is the guarantor of submission. |
|
Source of support
None |
|
Conflict of interest
Authors declare no conflict of interest. |
|
Copyright
© Laide Bello et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
|
|