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Case Report
 
Recurrent opportunistic infections in a post-transplant lymphoma patient
Ayelet Raz-Pasteur1, Yaakov Dickstein2, Ilana Oren3, Ayelet Eran4, Irit Avivi5, Khetam Hussein6
1Attending Physician, Internal Medicine A and Infectious Disease Unit, Rambam Medical Center, Haifa, Israel.
2Resident, Internal Medicine A, Rambam Medical Center, Haifa, Israel.
3Department head, Infectious Disease Unit, Rambam Medical Center, Haifa, Israel.
4Attending Physician, Department of Radiology, Rambam Medical Center, Haifa, Israel.
5Attending Physician, Department of Hematology, Rambam Medical Center, Haifa, Israel.
6Attending Physician, Infectious Disease Unit, Rambam Medical Center, Haifa, Israel.

doi:10.5348/ijcri-2012-12-235-CR-9

Address correspondence to:
Dr. Ayelet Raz-Pasteur
Internal Medicine Dept. A
Rambam Medical Center
Haaliyah Hasheniya 8, Haifa
Israel
Phone: 011-9724-854-2518
Fax: 011-9724-854-2721
Email: a_raz@rambam.health.gov.il

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How to cite this article:
Raz-Pasteur A, Dickstein Y, Oren I, Eran A, Avivi I, Hussein K. Recurrent opportunistic infections in a post-transplant lymphoma patient. International Journal of Case Reports and Images 2012;3(12):36–39.


Abstract
Introduction: Infections and graft-versus-host disease (GVHD) are the most notable problems after allogeneic stem cell transplantation (Allo SCT).
Case Report: A 50-year-old patient underwent an Allo SCT for transformed follicular lymphoma (t-FL). Transplant course of the patient was complicated by GVHD and recurrent, severe, opportunistic infections including pneumonia caused by two fungal pathogens simultaneously, recurrent bacteremia with no apparent source, septic arthritis caused by an unusual pathogen and eventually developed progressive multifocal leukoencephalopathy (PML).
Conclusion: This case illustrates the diversity of opportunistic infections affecting patients undergoing Allo SCT and the complexity involved in diagnosis and treatment of such infections.

Keywords: Allo SCT, GVHD, Opportunistic infections, Follicular lymphoma (FL), PML


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Author Contributions
Ayelet Raz-Pasteur – Conception and design, Acquisition of data, analysis and interpretation of data, drafting the article, Final approval of the version to be published
Yaakov Dickstein – Conception and design, Acquisition of data, Critical revision of the article, Final approval of the version to be published
Ilana Oren – Conception and design, analysis and interpretation of data, Critical revision of the article, Final approval of the article
Ayelet Eran – Analysis and interpretation of data; Drafting the article; Final approval of the article
Irit Avivi – Analysis and interpretation of data, Drafting the article, Final approval of the article
Khetam Hussein – Analysis and interpretation of data, Drafting the article, Final approval of the article
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© Ayelet Raz-Pasteur et al. 2012; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)