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Case Report
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| A patient with primary biliary cirrhosis and ulcerative colitis with progression to primary sclerosing cholangitis and colorectal cancer: A case report | ||||||
| Rui-Hua Shi1, Bo Hao1, Shun-Fu Xu1, Qi-Yun Tang1, Jian-Xia Jiang1 | ||||||
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1Department of Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
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| How to cite this article: |
| cholangitis and colorectal cancer: A case report. International Journal of Case Reports and Images 2012;3(12):11–15. |
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Abstract
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Introduction:
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon characterized by intermittent exacerbations and remissions. It can be associated with primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC) and complicated with colorectal cancer (CRC). We describe a complicated case of associaton of PBC and chronic UC, eventually progressed to PSC and CRC.
Case Report: A 41-year-old female was diagnosed as PBC based on liver biopsy 10 years before, and then UC was diagnosed too. Now symptoms of jaundice and abdominal pain aggravated. At last PSC, CRC were conformed. Conclusion: Prolonged inflammatory bowel disease (IBD) accompanied with PSC patient has high risk of CRC happening. More exploration is needed to gain insight into relationship between IBD, PBC, PSC and CRC. | |
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Keywords:
Primary biliary cirrhosis (PBC), Ulcerative colitis (UC), Primary sclerosing cholangitis (PSC), Colorectal cancer (CRC).
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Author Contributions
Rui-Hua Shi – Substantial contributions to conception and design, Acquisition of data, Drafting the article, revising it critically for important intellectual content, Final approval of the version to be published Bo Hao – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Final approval of the version to be published Shun-Fu Xu – Substantial contributions to conception and design, Acquisition of data, Revising the article critically for important intellectual content, Final approval of the version to be published Qi-Yun Tang – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Final approval of the version to be published Jian-Xia Jiang – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Rui-Hua Shi et al. 2012; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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