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Case Report
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| Synchronous nasal metastasis from pulmonary squamous cell carcinoma | ||||||
| Liling Zhang1, Junli Liu1, Tao Wang1, Gang Wu1 | ||||||
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1Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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| How to cite this article: |
| Zhang L, Liu J, Wang T, Wu G. Synchronous nasal metastasis from pulmonary squamous cell carcinoma. International Journal of Case Reports and Images 2012;3(10):32–34. |
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Abstract
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Introduction:
Squamous cell carcinoma spread from lung to the nasal cavity is extremely rare. Because of the identical appearance under light microscope, making a definitive diagnosis is a challenge when lesions are from both the nasal cavity and lung.
Case Report: We present a case of a 56-year-old patient with simultaneous malignancies in the lung and nasal cavity. On the basis of histologic analysis and radiographic features, a diagnosis of primary lung cancer with nasal metastsis was established. Since the histological appearance of the lung tumor and the nasal lesion is similar, the differential diagnosis between second primary and metastasis mainly depends on clinical criteria. However, the accuracy of this approach remains in question. Conclusion: It is a challenge to discern the true relationship of lung squamous cell carcinomas and nasal squamous cell carcinomas. The criteria currently employed in the distinction are mainly dependent on clinical, radiographic, and histologic grounds. Recent studies demonstrated that molecular genetic analysis can be a promising approach to solving this diagnosis dilemma. | |
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Key Words:
Squamous cell carcinoma, Lung cancer, Cancer of nasal cavity, Metastasis, Differential diagnosis
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Author Contributions:
Liling Zhang – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Junli Liu – Acquisition of data, Critical revision of the article, Final approval of the version to be published Tao Wang – Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published Gang Wu – Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission:
The corresponding author is the guarantor of submission. |
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Source of support:
None |
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Conflict of interest:
Authors declare no conflict of interest. |
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Copyright:
© Liling Zhang et al. 2012; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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