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| Pimary hyperparathyroidism as central giant cell granuloma of the jaws: Pre- and post-treatment pattern of clinical and radiographic presentation | ||||
| Nalini Aswath1, Pravda Chidambaranathan2 | ||||
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1Professor & Head of Department-Sree Balaji Dental College and Hospital, Chennai, Tamilnadu, India.
2Reader-Sathyabama Dental College and Hospital, Chennai Tamil Nadu, India. | ||||
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doi:10.5348/ijcri-2012-08-167-CII-14
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Address correspondence to: Dr. Nalini Aswath, "Mathuram" Plot No:161, #5 Murugu Nagar 5th street, Velachery Chennai, Tamil Nadu India - 600042 Phone: +91-044-22591519 Fax: 91–94441–61841 Email: naliniaswath@gmail.com | ||||
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| How to cite this article: |
| Aswath N, Chidambaranathan P. Pimary hyperparathyroidism as central giant cell granuloma of the jaws: Pre and post treatment pattern of clinical and radiographic presentation. International Journal of Case Reports and Images 2012;3(8):51–56. |
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Abstract
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Introduction:
The parathyroid glands regulate serum calcium and phosphorous levels by its secretion and maintenance, within physiological limits, of its hormone parathormone (PTH). Hyperparathyroidism is a metabolic disorder resulting from excessive secretion of parathyroid hormone. Hyper secretion might occur either due to a primary pathology in the glands (or) due to secondary causes. Central giant cell lesions occur in jaw bones.
Case Report: A 20-year-old boy reported with complaints of swelling in left maxilla. Intra orally swelling extended from left upper canine till left upper second premolar and caused expansion of the cortical plates. Intra oral radiograph and orthopantomograph showed a poorly defined radiolucent lesion in between left upper canine and left upper 1st premolar with multiple cystic cavities in the region of the symphysis, left body and right angle of mandible. The radiographs of long bones showed osteoporosis. Serum alkaline phosphatase level was raised. Histopathology was reported as central giant cell granuloma. Nuclear scan of parathyroid showed a functioning parathyroid adenoma. The swelling in left maxilla regressed on its own after the adenoma of the parathyroids was excised. Conclusion: Timely diagnosis of parathyroid adenoma results in total regression of intra oral swelling and further progression of osteoporosis and fractures of long bones can be prevented. | |
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Key Words:
Central giant cell granuloma, Brown tumor, Hyperparathyroidism
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Author Contributions:
Nalini Aswath – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Pravda Chidambaranathan – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission:
The corresponding author is the guarantor of submission. |
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Source of support:
None |
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Conflict of interest:
Authors declare no conflict of interest. |
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Copyright:
© Nalini Aswath et al. 2012; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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