Table of Contents    
Case Report
 
Lamotrigine is said to be safe but be cautious: A case report
Shri Niwash Jangir1, Rajeshwari Suthar2, AK Singhal3, Smita N Deshpande4
1Senior Research Associate, Department of Psychiatry, PGIMER-Dr. RML Hospital, New Delhi, India.
2Senior Resident, Department of Obstetric & Gynecology, ESIC Hospital, Government of India, New Delhi, India.
3Head, Department of Psychiatry, SP Medical College & AG Hospital, Bikaner, Rajasthan, India.
4Head, Department of Psychiatry, PGIMER-Dr. R.M.L. Hospital, New Delhi, India.

doi:10.5348/ijcri-2011-12-75-CR-5

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How to cite this article:
Jangir SN, Suthar R, Singhal AK, Deshpande SN. Lamotrigine is said to be safe but be cautious: A case report. International Journal of Case Reports and Images 2011;2(12):19-22.


Abstract
Introduction: Severe hypersensitivity reactions of lamotrigine are very uncommon conditions. We present this case of rapid development of toxic epidermal necrolysis.
Case Report: A 37-year-old female of bipolar affective disorder on lamotrigine presented with acute skin eruptions with fever which involved almost whole body in next 7-10 days. There was massive peeling of the skin involving more than 50% of the body surface.
Conclusion: The case was diagnosed as lamotrigine induced toxic epidermal necrolysis and treated conservatively. Conclusion: Watchfulness of the clinicians and educating the patient about the doses schedule and adverse reaction of lamotrigine is key to prevent severe cutaneous reactions.

Key Words: Lamotrigine, Bipolar affective disorder, Stevens - Johnson syndrome, Toxic epidermal necrolysis.

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Author Contributions:
Shri Niwash Jangir - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Rajeshwari Suthar - Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
A.K. Singhal - Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Smita N. Deshpande - Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
Authors declare no conflict of interest.
Copyright:
© Shri Niwash Jangir et al. 2011; This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see www.ijcasereportsandimages.com /copyright-policy.php for more information.) et. al. 2011; This article is distributed the terms of Creative Commons attribution 3.0 License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)