| Table of Contents |  |
|
Case Series
|
| Glycogen hepatopathy in children with poorly controlled type 1 diabetes |
| Hanh T. D. V1, Genna W. Klein2, Anthony Loizides3, Ping Zhou2, Qiang Liu4, Debra H. Pan3 |
|
1Department of Pediatrics, Bronx-Lebanon Hospital Center, Bronx, NY, United States.
2Division of Pediatric Endocrinology, Department of Pediatrics, The Children’s Hospital at Montefiore, Bronx, NY, United States. 3Division of Pediatric Gastroenterology, Department of Pediatrics, The Children’s Hospital at Montefiore, Bronx, NY, United States. 4Department of Pathology, The Children’s Hospital at Montefiore, Bronx, NY, United States. |
|
doi:10.5348/ijcri-2011-09-51-CS-1
|
|
Address correspondence to: Debra H. Pan Division of Pediatric Gastroenterology Department of Pediatrics The Children’s Hospital at Montefiore Bronx, NY 10467 USA. Phone: 1(718) 741 2332 Fax: 1(718) 515 5426 Email: dpan@montefiore.org |
|
[HTML Full Text]
[PDF Full Text]
|
| How to cite this article: |
| Vo HTD, Klein GW, Loizides A, Zhou P, Liu Q, Pan DH. Glycogen hepatopathy in children with poorly controlled type 1 diabetes. International Journal of Case Reports and Images 2011;2(9):1-4. |
|
Abstract
|
|
Introduction:
Glycogen hepatopathy has been described in children with poorly controlled type 1 diabetes. Diabetic patients with hepatomegaly and abnormal liver enzymes have often been assumed to have non-alcoholic steatohepatitis rather than glycogen hepatopathy. It is important to recognize and distinguish glycogen hepatopathy from non- alcoholic steatohepatitis as it impacts the management and long-term prognosis.
Case Series: We describe four cases of children with poorly controlled type 1 diabetes mellitus who developed glycogen hepatopathy, and review the available literature. Conclusion: Pediatricians should raise awareness of this potentially reversible liver complication in children with poorly controlled T1DM. It has been suggested that diabetic patients with hepatomegaly and elevated liver enzymes be given a trial of improved glycemic control prior to more invasive investigation. | |
|
Key Words:
Children, Hepatomegaly, Diabetes, Glycogen hepatopathy
| |
| [HTML Full Text] [PDF Full Text] |
|
Author Contributions:
Hanh T. D. Vo - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published. Genna W. Klein - Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published. Anthony Loizides - Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published. Ping Zhou - Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published. Qiang Liu - Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published. Debra H. Pan - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published. |
|
Guarantor of submission:
The corresponding author is the guarantor of submission. |
|
Source of support:
None |
|
Conflict of interest:
Authors declare no conflict of interest. |
|
Copyright:
© Hanh T. D. Vo et al. 2011; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
|
|