Table of Contents    
Case Report
 
Ostemyelitis of the clivus due to Fusobacterium necrophorum
Amir Fallahian1, Neal Desai2, Mary Anne Jackson3, Jean Claude Decarrie4, Douglas C Rivard5
1Radiologist, Department of Radiology, University of Missouri, Columbia, MO, USA.
2Medical Student, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
3Professor of Pediatrics, Department of Infectious Disease, Children's Mercy Hospital and Clinics and the University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
4Radiologist, CHU Ste-Justine, Imagerie Medicale, Montreal, Quebec, Canada.
5Assistant Professor of Radiology, Department of Radiology, Children's Mercy Hospital and Clinics and the University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.

doi:10.5348/ijcri-2011-07-45-CR-5

Address correspondence to:
Douglas C. Rivard
Childrens Mercy Hospital and Clinics
Department of Radiology
2401 Gillham Rd
Kansas City, MO 64108
USA
Phone: 1-816-234-3270
Email: dcrivard@cmh.edu

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How to cite this article:
Fallahian A, Desai N, Jackson MA, Decarrie JC, Rivard DC. Ostemyelitis of the clivus due to Fusobacterium necrophorum. International Journal of Case Reports and Images 2011;2(7):17-20.


Abstract
Introduction: Septic jugular thrombosis with secondary osteomyelitis of the clivus due to Fusobacterium necrophorum is a rare complication of Lemierre's syndrome. Other complications that can occur include cavernous sinus thrombosis and cerebral arterial vasospasm.
Case Report: We present a case of a young girl illustrating the clinical findings of Lemierre's syndrome in addition to other complications that may occur. Retropharyngeal infection with internal jugular venous thrombosis was present in this case along with Fusobacterium necrophorum septicemia. Lemierre's syndrome consists of oropharyngeal infection with internal jugular vein thrombosis, anaerobic septicemia and septic embolization to multiple organ systems. Osteomyelitis of the clivus is a rare, but important complication associated with this syndrome. Fusobacterium necrophorum, the usual pathogen implicated in Lemierre's syndrome has rarely been known to be the sole pathogen implicated in childhood osteomyelitis secondary to septic jugular vein thrombosis. It is important to recognize some of the complications of septic jugular vein thrombosis to reduce morbidity and mortality.
Conclusion: Awareness of the clinical and radiologic findings that may be seen in pediatric retropharyngeal infections along with awareness of the possible complications can help guide early treatment or surgical intervention.

Key Words: Osteomyelitis, Clivus, Fuso-bacterium Necrophorum, Lemierre's syndrome

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Author Contributions:
Amir Fallahian - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Neal Desai - Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Mary Anne Jackson - Group 1 - Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Jean Claude Decarrie - Acquisition of data, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Douglas C. Rivard - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
Authors declare no conflict of interest.
Copyright:
© Douglas C. Rivard et al. 2011; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)