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CASE SERIES
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| Hereditary gingival fibromatosis: Report of four generation pedigree |
| Vishnoi SL1 |
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1Senior Lecturer, Department of Periodontics, Manubhai patel Dental College and Hospital, Vadodara- 431001, Gujarat (INDIA).
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doi:10.5348/ijcri-2011-06-36-CS-1
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Address correspondence to: Dr. Shivlal L. Vishnoi Manubhai patel Dental College and Hospital Vishwajyoti Ashram Near Vidhyakunj School Munjmahuda Vadodara 7 Gujarat India Phone: 91-9586869196 Email: Vishnoi_shivlal@yahoo.com |
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| How to cite this article: |
| Vishnoi SL. Hereditary gingival fibromatosis: Report of four generation pedigree. International Journal of Case Reports and Images 2011;2(6):1-5. |
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Abstract
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Introduction:
Gingival enlargement is defined as an overgrowth or increase in size of gingivae. Gingival enlargement is associated with multiple factors including inflammation, medications, neoplasia, hormonal disturbances and heredity, rarely. Hereditary gingival fibromatosis (HGF) is a rare gingival lesion (1 in 7,50,000) that presents as localized or generalized fibrotic enlargement of the attached gingivae as well as the gingival margin and interdental papillae. The gingiva is characterized as pink, firm and fibrous, with little tendency to bleed. It causes aesthetic disfigurement, speech disturbances, abnormal tooth movement and dental occlusion problems. HGF can present as an isolated feature or as a part of the syndrome. HGF inheritance is transmitted through both autosomal dominant and recessive modes.
Case Series: This report presents hereditary gingival fibromatosis in a family, described with multiple affected subjects in four generations, consistent with an autosomal dominant mode of inheritance Conclusion: It is a unique report of pedigree presenting gingival enlargement in four generation. Very few papers are published previously on this topic. Like other reported family, in current family variable expression of HGF was seen because most of the affected persons had generalized gingival enlargement while some had localized involvement. | |
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Key Words:
Hereditary gingival fibromatosis; Autosomal dominant; Aesthetic disfigurement
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Author Contributions:
Shivlal L. Vishnoi - Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission:
The corresponding author and the first author are the guarantor of submission. |
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Source of support:
None |
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Conflict of interest:
The author(s) declare no conflict of interests |
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Copyright:
© Shivlal L. Vishnoi et al. 2010; This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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