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Case Report
 
Primary thyroid diffuse large B cell lymphoma: A case report
Tej Prakash Soni1, Upendra Nandwana2, Lalit Mohan Sharma3, Anil Kumar Gupta4, Naresh Jakhotia1, Shantanu Sharma5
1Consultant, Department of Radiation Oncology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Rajasthan, India
2Senior Resident, Department of Radiation Oncology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Rajasthan, India
3Senior Consultant, Department of Medical Oncology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Rajasthan, India
4Senior Consultant, Department of Surgical Oncology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Rajasthan, India
5Associate Professor, Department of Radiotherapy, S.M.S. Medical College and Hospital, Jaipur, Rajasthan, India

Article ID: Z01201708CR10816TS
doi:10.5348/ijcri-201777-CR-10816

Address correspondence to:
Tej Prakash Soni
Consultant, Department of Radiation Oncology
Bhagwan Mahaveer Cancer Hospital and Research Centre
JLN Road, Jaipur, Rajasthan
India, Pincode 302017

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How to cite this article
Soni TP, Nandwana U, Sharma LM, Gupta AK, Jakhotia N, Sharma S. Primary thyroid diffuse large B cell lymphoma: A case report. Int J Case Rep Images 2017;8(8):533–537.


ABSTRACT

Introduction: Primary thyroid lymphoma is a unique and rare entity. We report a rare case of primary thyroid lymphoma (diffuse large B cell lymphoma) in a male patient.
Case Report: A 40-year-old male presented with complaints of rapidly progressive mass in left thyroid region neck. True cut biopsy from the thyroid lesion and immunohistochemistry study was reported as primary thyroid lymphoma. He was treated with chemotherapy followed by radiotherapy. After one year of the treatment his disease is well controlled with no evidence of recurrence or residual tumor. Differential diagnosis includes Hashimoto’s thyroiditis, anaplastic thyroid carcinoma, and secondary thyroid lymphoma. Hashimoto’s thyroiditis is commonly associated with primary thyroid lymphoma.
Conclusion: Accurate and correct diagnosis of primary thyroid lymphoma is very important as its management is different from other thyroid malignancies. It is treated by combination of chemotherapy and radiotherapy. The role of surgery is questionable. Palliative thyroidectomy can be done in patients with obstructive symptoms.

Keywords: Differential diagnosis, Primary Thyroid lymphoma, Rare



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Author Contributions
Tej Prakash Soni – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Upendra Nandwana – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Lalit Mohan Sharma – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Anil Kumar Gupta – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Naresh Jakhotia – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Shantanu Sharma – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Tej Prakash Soni et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.