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Case Report
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| Cannabis consumption before surgery may be associated with increased tolerance of anesthetic drugs: A case report | ||||||
| Georg Richtig1, Götz Bosse2, Friederike Arlt3, Christian von Heymann4 | ||||||
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1MD, Research Fellow, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
2MD, Consultant, Department of Anaesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow - Klinikum, Charité - University Medicine Berlin, Germany. 3MD, Registrar, Department of Anaesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow - Klinikum, Charité - University Medicine Berlin, Germany. 4MD, DEAA, Professor, Department of Anaesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow - Klinikum, Charité - University Medicine Berlin, Germany. | ||||||
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| How to cite this article |
| Richtig G, Bosse G, Arlt F, von Heymann C. Cannabis consumption before surgery may be associated with increased tolerance of anesthetic drugs: A case report. Int J Case Rep Images 2015;6(7):436–439. |
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Abstract
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Introduction:
Cannabis is the most commonly used illicit drug worldwide in adults. Several studies suggest an interaction of cannabis intake and anesthetic drugs like propofol and thiopental, but the pharmacodynamic interaction between cannabis and commonly used anesthetic drugs is still not well understood.
Case Report: A 37-year- old male patient with a history of regular cannabis consumption and cannabis intake the day before surgery was admitted for an arthroscopic shoulder stabilization. Induction of anesthesia required large doses of propofol, thiopental and sevoflurane. Maintenance was achieved with the additional application of nitrous oxide to provide clinical tolerance of the surgical procedure. Return of consciousness and the postoperative course were uneventful. Conclusion: History of cannabis intake should be taken into routine preoperative assessment and patients should be closely monitored by experienced anesthesia staff for adequate anesthetic depth and analgesia. | |
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Keywords:
Anesthesia, Cannabis, Interaction, Pharmacodynamics
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Author Contributions
Georg Richtig – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Götz Bosse – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Friederike Arlt – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published Christian von Heymann – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Georg Richtig et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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