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Case Report
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| Primary serous carcinoma of peritoneum: A case report | ||||||
| Shelly Sehgal1, Reena Agarwal1, Prashant Goyal2, Sompal Singh1 Vinita Kumar3 Ruchika Gupta4 | ||||||
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1MD, Department of Pathology, Swami Dayanand Hospital, Shahdara, New Delhi, India.
2DCP, Department of Pathology, Swami Dayanand Hospital, Shahdara, New Delhi, India. 3MD, Department of Gynecologic Oncology, Delhi State Cancer Institute, Dilshad Garden, New Delhi, India. 4MD, Department of Pathology, Chacha Nehru Bal Chiktsalaya, New Delhi, India. | ||||||
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| How to cite this article: |
| Sehgal S, Agarwal R, Goyal P, Singh S, Kumar V, Gupta R. Primary serous carcinoma of peritoneum: A case report. International Journal of Case Reports and Images 2012;3(10):16–20. |
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Abstract
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Introduction:
Primary serous papillary carcinoma of the peritoneum (PSPCP) is a rare malignant epithelial tumor that is histologically indistinguishable from papillary serous carcinoma of the ovary (PSCO). It is defined as primary tumor of peritoneum that diffusely involves the peritoneal surface but spares or only superficially invades the ovaries. Better recognition of this entity in recent years has contributed to an increasing diagnostic frequency.
Case Report: A case of 50-year-old female who was presented with abdominal distension and pain is reported. Ascitic fluid cytology showed malignant cells favoring papillary serous adenocarcinoma. Preoperative serum CA-125 was markedly elevated. CECT scan showed omental thickening with normal uterus and ovaries. Exploratory laparotomy revealed massive ascites with extensive peritoneal deposits and normal sized ovaries. Histopathology confirmed diagnosis of PSPCP with surface involvement of both the ovaries. Conclusion: PSPCP is a rare neoplasm, histologically indistinguishable from PSCO. We presented this case report to emphasise that peritoneum, can also be a primary site of malignancy and that it presents and is managed just like primary ovarian cancer. Pre-op diagnosis of this entity is difficult. Histopathology is mandatory to confirm the diagnosis. | |
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Key Words:
Papillary, Serous, Peritoneum, Ovary, CA-125
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Author Contributions:
Shelly Sehgal – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Reena Agarwal – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Prashant Goyal – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Sompal Singh – Drafting the article, Critical revision of the article, Final approval of the version to be published Vinita Kumar – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Ruchika Gupta – Drafting the article, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission:
The corresponding author is the guarantor of submission. |
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Source of support:
None |
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Conflict of interest:
Authors declare no conflict of interest. |
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Copyright:
© Shelly Sehgal et al. 2012; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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