Case Report


Severe opportunistic infections in extrapulmonary sarcoidosis

,  ,  ,  ,  ,  

1 Department of Internal Medicine, Costa del Sol Hospital Spain

2 Department of Internal Medicine, Costa del Sol Hospital Spain

3 Department of Microbiology, Costa del Sol Hospital Spain

4 Department of Pathology, Costa del Sol Hospital Spain

5 Department of Radiology, Costa del Sol Hospital Spain

6 Department of Angiology and Vascular Surgery, Virgen de la Victoria Hospital Spain

Address correspondence to:

Carlos Romero-Gómez

Mail Address: C/ Parque 16, 2A, Málaga,

Spain, 29018

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Article ID: 100950Z01CG2018

doi: 10.5348/100950Z01CG2018CR

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How to cite this article

Romero-Gómez C, Aguilar-García JA, Montiel-Quezel N, Salguero TP, Del Álamo FFG, Rafael GM. Severe opportunistic infections in extrapulmonary sarcoidosis. Int J Case Rep Images 2018;9:100949Z01CG2018.

ABSTRACT


Introduction: Sarcoidosis is a chronic multisystemic disease of unknown etiology characterized by noncaseating granulomas that most frequently affect the lungs, but frequently has extrapulmonary manifestations. Treatment of symptomatic sarcoidosis, glucocorticoids and immunosuppressants, may be associated with an increased risk of infection.

Case Report: We report a patient with extrapulmonary sarcoidosis on immunosuppressive therapy who had polymicrobial infection, including Mycobacterium tuberculosis and Mycobacterium genavense complicated by infected aortic aneurysm.

Conclusion: In patients with sarcoidosis with persistent fever, a possible over-infection, including opportunistic agents should be evaluated. Infected tuberculous aneurysm is very unusual. This is the first case in the literature of tuberculous aneurysm associated with anti-TNF treatment.

Keywords: Anti-TNF therapy, Infected aneurysm, Mycobacterium tuberculosis, Mycobacterium genavense, Sarcoidosis

SUPPORTING INFORMATION


Author Contributions:

Carlos Romero-Gómez - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Josefa Andréa Aguilar-Garc - Acquisition of data, Drafting the article, Final approval of the version to be published

Natalia Montiel-Quezel - Acquisition of data, Drafting the article, Final approval of the version to be published

Teresa Pereda Salguero - Acquisition of data, Drafting the article, Final approval of the version to be published

Fátima Fernández Gutiérre - Acquisition of data, Drafting the article, Final approval of the version to be published

Gomez-Medialdea Rafael - Acquisition of data, Drafting the article, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source Of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this case report.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2018 Carlos Romero-Gómez et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.


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