Case Report
 
Ductal Carcinoma-in-situ within fibroadenoma of the breast: A case report with literature review
Sana Zeeshan1, Sabeeh Siddique2, Nazia Riaz3
1Lecturer, Section of Breast Surgery, Department of Surgery, The Aga Khan University, Karachi, Pakistan
2Senior Instructor, Section of Histopathology, Department of Pathology and Laboratory Medicine, The Aga Khan University, Karachi, Pakistan
3Assistant Professor, Section of Breast Surgery, Department of Surgery, The Aga Khan University, Karachi, Pakistan

Article ID: 100916Z01SZ2018
doi: 10.5348/100916Z01SZ2018CR

Corresponding Author:
Dr. Nazia Riaz,
Department of Surgery,
The Aga Khan University,
P.O. Box 3500,
Stadium Road Karachi,
Pakistan, Postal Code: 74800

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How to cite this article
Zeeshan S, Siddique S, Riaz N. Ductal Carcinoma-in-situ within fibroadenoma of the breast: A case report with literature review. Int J Case Rep Images 2018;9:100916Z01SZ2018.


ABSTRACT

Introduction: Fibroadenoma is a most commonly diagnosed benign tumor of the breast with highest occurrence in adolescent and young women, but its coexistence with ductal carcinoma in-situ (DCIS) is extremely rare and infrequently reported.

Case Report: We report a case of 34-year-old pregnant female who was diagnosed with DCIS within fibroadenoma on wide local excision. The diagnosis of DCIS was not identified on core biopsy. The patient was subsequently managed with radiation followed by endocrine therapy as DCIS was positive for expression of estrogen and progesterone receptors.

Conclusion:> Diagnosis of DCIS within fibroadenoma is a rare presentation and requires extensive tissue sampling by pathologist in order to avoid missing it. As this is a rare entity, management and follow-up remains a challenge in the absence of established guidelines.

Keywords: Breast lump, Case report, Ductal carcinoma in-situ, Fibroadenoma


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Author Contributions
Sana Zeeshan – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sabeeh Siddique – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Nazia Riaz – Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of Submission
The corresponding author is the guarantor of submission.
Source of Support
None
Consent Statement
Written informed consent was obtained from the patient for publication of this case report.
Conflict of Interest
Author declares no conflict of interest.
Copyright
© 2018 Sana Zeeshan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.