Successful treatment of pneumomediastinum in a patient with interstitial lung disease due to anti-synthetase syndrome: A case report

Abstract is not required for Clinical Imagesis not required for Clinical Images (This page in not part of the published article.) International Journal of Case Reports and Images, Vol. 8 No.8, August 2017. ISSN – [0976-3198] Int J Case Rep Images 2017;8(8):564–566. www.ijcasereportsandimages.com Cho et al. 564 CASE REPORT OPEN ACCESS Successful treatment of pneumomediastinum in a patient with interstitial lung disease due to anti-synthetase syndrome: A case report Roy Cho, Erhan H. Dincer, Rade Tomic, Hyun Kim


DISCUSSION
Pneumomediastinum (PNM) is a rare complication of anti-synthetase syndrome with only three cases reported since 1986 [1][2][3]. The associated one-month mortality is 25%, which highlights the need for effective management [4]. The management of PNM in interstitial lung disease is based on case reports and experience forming expert opinion. However, the best management requires understanding the pathogenesis [5]. Several mechanisms of PNM in interstitial lung disease have been proposed including the Macklin effect, worsening vasculitis

CLINICAL IMAGE PEER REVIEWED | OPEN ACCESS
leading to airway rupture, and weakened alveolar walls from immunosuppression [6]. In this case, reducing immunosuppression suggested that weakened alveolar walls was a factor and using high-concentration oxygen and cough suppressant decidedly contributed to the full recovery. Notably, this is the second case in literature that has reported success using high-concentration oxygen for the treatment of PNM [7].

CONCLUSION
We report a case of pneumomediastinum in a patient with anti-synthetase syndrome who was successfully

Edorium Journals: An introduction
Why should you publish with Edorium Journals?
In less than 10 words: "We give you what no one does".

Vision of being the best
We have the vision of making our journals the best and the most authoritative journals in their respective specialties. We are working towards this goal every day.

Exceptional services
We care for you, your work and your time. Our efficient, personalized and courteous services are a testimony to this.

Editorial review
All manuscripts submitted to Edorium Journals undergo pre-processing review followed by multiple rounds of stringent editorial reviews.

Peer review
All manuscripts submitted to Edorium Journals undergo anonymous, double-blind, external peer review.

Early view version
Early View version of your manuscript will be published in the journal within 72 hours of final acceptance.

Manuscript status
From submission to publication of your article you will get regular updates about status of your manuscripts.

Favored author program
One email is all it takes to become our favored author. You will not only get 15% off on all manuscript but also get information and insights about scholarly publishing.

Institutional membership program
Join our Institutional Memberships program and help scholars from your institute make their research accessible to all and save thousands of dollars in publication fees.

Our presence
We have high quality, attractive and easy to read publication format. Our websites are very user friendly and enable you to use the services easily with no hassle.
We request you to have a look at our website to know more about us and our services. Please visit: www.edoriumjournals.com We welcome you to interact with us, share with us, join us and of course publish with us.

Invitation for article submission
We sincerely invite you to submit your valuable research for publication to Edorium Journals.

Six weeks
We give you our commitment that you will get first decision on your manuscript within six weeks (42 days) of submission. If we fail to honor this commitment by even one day, we will give you a 75% Discount Voucher for your next manuscript.

Four weeks
We give you our commitment that after we receive your page proofs, your manuscript will be published in the journal within 14 days (2 weeks). If we fail to honor this commitment by even one day, we will give you a 75% Discount Voucher for your next manuscript.