Case Report
 
Necrotizing fasciitis of lower limb: Is it ischemia or E. coli infection?
Takahiro Matsuo2, Hiroki Mochizuki1, Atsushi Mizuno1, Keiichi Furukawa2, Yutaro Nishi1, Koichiro Niwa1
1Department of Cardiology, St. Luke's International Hospital, Tokyo, Japan.
2Department of Infectious Diseases, St. Luke's International Hospital, Tokyo, Japan.

Article ID: Z01201611CR10709SS
doi:10.5348/ijcri-2016121-CR-10709

Address correspondence to:
Takahiro Matsuo
MD, Department of Infectious Diseases
St. Luke's International Hospital, Tokyo, Japan
9-1, Akashi-cho, Chuo-ku, Tokyo
Japan, 104-8560

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How to cite this article
Matsuo T, Mochizuki H, Mizuno A, Furukawa K, Nishi Y, Niwa K. Necrotizing fasciitis of lower limb: Is it ischemia or E. coli infection? Int J Case Rep Images 2016;7(11):701–705.


Abstract
Introduction: Necrotizing fasciitis (NF) is a life-threatening soft-tissue infection characterized by a fulminant course and high mortality. Diagnosis of necrotizing fasciitis is often difficult, because nascent necrotizing fasciitis often appears deceptively benign and lack specific diagnostic clues. In addition, the manifestations of NF are similar to those of acute limb ischemia. Here, we introduce the case of necrotizing fasciitis accompanied with acute limb ischemia on left lower leg.
Case Report: A 71-year-old male with a history of stomach cancer complained of vomiting and dyspnea one day before admission to our hospital. Two days after admission, his left lower extremity whitened and became edematous. Contrast-enhanced computed tomography revealed severe stenosis of the left common iliac artery. We were unable to rule out acute limb ischemia and performed endovascular revascularization. However, the leg did not improve and major amputation was performed. The leg pathology was suggestive of necrotizing fasciitis.
Conclusion: We should not forget the possibility that any systemic infection can result in necrotizing fasciitis even if the patients have high risk of acute limb ischemia.

Keywords: Acute limb ischemia, E. coli, Escherichia coli, Necrotizing fasciitis, Pneumonia


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Author Contributions
Takahiro Matsuo – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hiroki Mochizuki – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Atsushi Mizuno – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Keiichi Furukawa – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Yutaro Nishi – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Koichiro Niwa – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Takahiro Matsuo et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.