Case Report
 
Micro invasive papillary thyroid lesion in a post living donor liver transplant patient: A case report
Khaled Abdel wahab1, Essam Attia1, Mohammad Arafa2, Mohamed El Sorogy3, Mohamed Abdel Wahab3
1Surgical Oncology Unit, Mansoura Oncology center, Mansoura University.
2Pathology Department, Mansoura University, Egypt.
3Gastroenterology center, Mansoura university, Egypt.

Article ID: Z01201605CR10645KW
doi:10.5348/ijcri-201657-CR-10645

Address correspondence to:
Khaled Abdel Wahab
Lecturer of Surgical Oncology
Surgical Oncology Unit, Mansoura Oncology Center
Mansoura University
Egypt

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How to cite this article
Wahab KA, Attia E, Arafa M, El Sorogy M, Wahab MA. Micro invasive papillary thyroid lesion in a post living donor liver transplant patient: A case report. Int J Case Rep Imag 2016;7(5):323–326.


Abstract
Introduction: Liver transplant recipients are at increased risk of developing de novo malignancies. Skin cancers and lymphoma are common in adult transplant recipients, while post-transplant lymphoproliferative disorder (PTLD) is the most common concern in pediatric transplant recipients. De novo malignancy is a well-recognized complication of solid organ transplantation and associated immunosuppression. The development of such malignancies can be caused by a multifactorial combination of individual and regional predispositions to malignancy, pretransplantation disease states, recipient viral status, and the use and intensity of various immunosuppressive regimens to maintain allografts.
Case Report: This report describes a papillary microinvasion of the thyroid in an adult Egyptian male following liver transplantation and declares the need for a high level of suspicion and careful investigation into any abnormal lesion in the long-term follow-up of solid organ transplant patients.
Conclusion: Care should be taken towards any significant symptom or sign suspicious for malignancy for post-transplant patients. The idea of having a routine screening program to detect de novo tumors for those patients should be discussed more.

Keywords: De novo malignancy, Immunosuppressive therapy, Liver transplant, Thyroid lesion


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Author Contributions
Khaled Abdel Wahab – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Essam Attia – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mohammad Arafa – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mohamed El Sorogy – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mohamed Abdel Wahab – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Khaled Abdel Wahab et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



About The Authors

Khaled Mohamed Abdel Wahab is a lecturer of surgical oncology at Mansoura oncology center, Mansoura university in Egypt. He earned the undergraduate degree (M.B.B.CH) from Faculty of medicine, Mansoura university in 2005, Master degree of general surgery in 2010, Master of breast reconstruction from La Sapienza university in Rome, Italy in 2013 and MD degree from Mansoura faculty of medicine in 2015. He has published 13 research papers in national and international academic journals and is an editorial member in four international journals. His research interests include breast surgery and head and neck surgery.



Essam Attia is working in Surgical Oncology Unit, Mansoura Oncology center, Mansoura University.



Mohammad Arafa is working in Pathology Department, Mansoura University, Egypt.



Mohamed El Sorogy is working in Gastroenterology center, Mansoura university, Egypt.



Mohamed Abdel Wahab is working in Gastroenterology center, Mansoura university, Egypt.