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Case Report
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| Aspergillus as a rare cause of non-healing traumatic breast wound | ||||||
| Sana Zeeshan1, Syed Faisal Mahmood2, Abida K. Sattar3 | ||||||
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1FCPS, Fellow Breast Surgery, Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan.
2MD, Associate Professor, Infectious Diseases, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan. 3MD, Assistant Professor, Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan. | ||||||
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| How to cite this article |
| Zeeshan S, Mahmood SF, Sattar AK. Aspergillus as a rare cause of non-healing traumatic breast wound. Int J Case Rep Imag 2016;7(4):235–239. |
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Abstract
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Introduction:
Aspergillus is an opportunistic fungal infection in immunocompromised hosts with a very rare occurrence in breast tissue.
Case Report: We report a case of Aspergillus flavus, identified within a non-healing ulcer in the breast of an immunocompromised host. The patient was a 63-year old lady with diabetes mellitus and severe rheumatoid arthritis requiring oral prednisolone therapy. She had developed a pressure ulcer on her right breast secondary to an upper extremity cast placed for conservative management of a humerus fracture. This pressure ulcer failed to improve despite multiple debridements, local wound care and antibiotic treatment. Tissue biopsy from the debridement specimen revealed fungal hyphae without evidence of malignancy. Formal fungal cultures confirmed this to be Aspergillus flavus. She was started on oral Itraconazole along with local wound care. She later succumbed to gram negative sepsis and Disseminated intravascular coagulation (DIC). Extensive literature search to identify causes of non-healing traumatic breast wounds revealed a few case reports only. Conclusion: Aspergillus can present with extensive soft tissue or breast involvement in immune suppressed individuals and should be considered in patients with a non-healing breast wound with a high index of suspicion. | |
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Keywords:
Aspergillus, Breast wound, Immune compromised, Non-healing
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Author Contributions
Sana Zeeshan – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Syed Faisal Mahmood – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Final approval of the version to be published Abida K. Sattar – Substantial contributions to conception and design, Acquisition of data, Drafting the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2016 Sana Zeeshan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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