Case Report
 
Rhabdomyolysis and acute kidney injury in Salmonella gastroenteritis: A case report
Ziqiang Zhu1, Sina Aghaie1, Andrei Bandarchuk1, Anjula Gandhi1
1Internal Medicine, Brookdale University Hospital and Medical Center, One Brookdale Plaza, Brooklyn, NY, USA.

doi:10.5348/ijcri-201541-CR-10502

Address correspondence to:
Ziqiang Zhu
MD, Internal Medicine, Brookdale University Hospital and Medical Center
One Brookdale Plaza, Brooklyn
NY 11212
USA

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How to cite this article
Zhu Z, Aghaie S, Bandarckuk A, Gandhi A. Rhabdomyolysis and acute kidney injury in Salmonella gastroenteritis: A case report. Int J Case Rep Images 2015;6(4):233–238.


Abstract
Introduction: Although infection by Salmonella has been commonly associated to diarrhea, complications such as cholecystitis, pancreatitis, acute pyelonephritis, osteomyelitis, myocarditis, encephalopathy, and multi-organ failure have been rarely reported.
Case Report: Herein, we report a case of S. enteritidis gastroenteritis complicated by rhabdomyolysis and acute kidney injury, which was successfully treated with hydration and antibiotics without dialysis. In this report, we reviewed all the previously published cases of rhabdomyolysis associated with Salmonella infection in English literatures and discussed the prevalence, pathogenesis and treatment.
Conclusion: Rhabdomyolysis was thought to be a rare complication of Salmonella infection. However, due to the variable manifestations that depend upon the extent and severity of muscle damage, rhabdomyolysis is perhaps under diagnosed as an extra-intestinal manifestation of Salmonella infection. Therefore, it is critical to recognize the condition promptly, initiate early antibiotics treatment and provide good supportive care. A high index of suspicion may help to reduce significant co-morbidities associated with the development of rhabdomyolysis in Salmonella infection.

Keywords: Acute kidney injury, Gastroenteritis, Rhabdomyolysis, Salmonella infection


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Author Contributions
Ziqiang Zhu – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sina Aghaie – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Andrei Bandarchuk – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Anjula Gandhi – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2015 Ziqiang Zhu et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



About The Authors

Ziqiang Zhu is a resident in the Department of Medicine, the Brookdale University Hospital and Medical Center, NY, USA. He earned M.D. degree from Zhejiang University School of Medicine, Hangzhou, China and Master's degree from Peking Union Medical College, Beijing, China. He received 5-year postdoctoral training at both University of Louisville and National Cancer Institute/National Institutes of Health. He has published over 10 original research papers in international academic journals. His research interests include cancer immunology and developing novel targets for cancer treatment.



Sina Aghaie is a resident in the Department of Medicine, the Brookdale University Hospital and Medical Center, NY, USA.



Andrei Bandarchuk is a chief resident in the Department of Medicine, the Brookdale University Hospital and Medical Center, NY, USA.



Anjula Gandhiis a faculty in the Department of Medicine, the Brookdale University Hospital and Medical Center, NY, USA.