Case Report
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Ameloblastic carcinoma of the mandible: A case report | ||||||
Soumithran C.S.1, Sudha S.2, Ikram Bin Ismail P.T.3, Ambadas4, Jibin Jose Tom3, Seeja P.5 | ||||||
1MDS, Professor and Head, Department of Oral and Maxillofacial Surgery, Govt. Dental College, Kozhikode, Kerala, India.
2MDS, Professor and Head, Department of Oral and Maxillofacial Pathology, Govt. Dental College, Kozhikode, Kerala, India. 3Junior Resident (Post Graduate Student), Department of Oral and Maxillofacial Surgery, Govt. Dental College, Kozhikode, Kerala, India. 4MDS, Senior Resident/Lecturer, Department of Oral and Maxillofacial Surgery, Govt. Dental College, Kozhikode, Kerala, India. 5Lecturer Trainee, Department of Oral and Maxillofacial Surgery, Govt. Dental College, Kozhikode, Kerala, India. | ||||||
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How to cite this article |
Soumithran CS, Sudha S, Ikram Bin Ismail PT, Ambadas, Tom JJ, Seeja P. Ameloblastic carcinoma of the mandible: A case report. Int J Case Rep Images 2015;6(1):11–15. |
Abstract
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Introduction:
Ameloblastic carcinoma is an extremely rare, malignant epithelial tumor of the jaws with a poor prognosis. The most common site of occurrence is the posterior mandible. Clinically, it is very aggressive and has potential for extensive local destruction. Majority of the cases arise de novo (primary type), but a few cases arise from a pre-existing ameloblastoma (secondary type).
Case Report: A 30-year-old female presented with a chief complaint of swelling on the left side of the face for the past one year. An incisional biopsy was performed and the histopathology was consistent of ameloblastic carcinoma. On the basis of the histopathology report, left hemimandibulectomy was done taking a safe margin of 2 cm and the defect was reconstructed using titanium reconstruction plate. Chemotherapy and radiotherapy were not advised. The patient is under regular follow-up. No recurrence nor metastases reported during the follow-up period. Conclusion: Early diagnosis and wide local excision on the primary site is the treatment of choice. The risk of malignant transformation should always be considered when a classic ameloblastoma is diagnosed and the prompt definitive management of an ameloblastoma is essential to eliminate this risk. Finally, meticulous, long-term follow-up is mandatory because recurrence and metastasis in the lung and regional lymph nodes have been reported. | |
Keywords:
Ameloblastoma, Ameloblastic carcinoma, Carcinoma, Odontogenic tumor
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Author Contributions
Soumithran C.S. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Sudha S. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Ikram Bin Ismail P.T. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Ambadas – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Jibin Jose Tom – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Seeja P. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
Guarantor of submission
The corresponding author is the guarantor of submission. |
Source of support
None |
Conflict of interest
Authors declare no conflict of interest. |
Copyright
© 2015 Soumithran C.S. et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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