International Journal of Case Reports and Images - IJCRI - Case Reports, Case Series, Case in Images, Clinical Images

     
Case Report
 
Mixed connective tissue disorder: A case report
Rishi Katewa1, Jakhar RS2, Barala GL3
1MBBS, Medical Officer, General Medicine, Barala Hospital and Research Center, Jaipur, Rajasthan, India.
2MBBS, MD, Attending Physician, General Medicine, Barala Hospital and Research Center, Jaipur, Rajasthan, India.
3MBBS, MD, Attending Physician and Director, Barala Hospital and Research Center, Jaipur, Rajasthan, India.

doi:10.5348/ijcri-2014116-CR-10427

Address correspondence to:
Dr. Rishi Katewa
117, Everest Vihar, Kings Road
Jaipur, Rajasthan, Postal Code- 302019
India
Phone: +919571069175
Email: rishikatewa88@gmail.com

Access full text article on other devices

  Access PDF of article on other devices

[HTML Full Text]   [PDF Full Text] [Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar]


How to cite this article
Katewa R, Jakhar RS, Barala GL. Mixed connective tissue disorder: A case report. Int J Case Rep Images 2014;5(9):650–655.


Abstract
Introduction: Mixed connective tissue disorder is rarely reported in India. It is a disease with overlapping features of many connective tissue disorders and the presence of anti-U1RNP. We present a case with dyspnea and generalized swelling as the initial presentation that led to the diagnosis of mixed connective tissue disorder.
Case Report: A 60-year-old female came with initial complains of progressive dyspnea limiting her daily activities, palpitations, generalized body swelling since 15 days and fever since one week. Detailed history and physical examination revealed bluish discoloration of fingers on exposure to low temperature, dysphagia and difficulty opening the mouth and sclerodactyly. Laboratory workup and radiography concluded the diagnosis of mixed connective tissue disorder. Pulmonary function tests suggested restrictive lung disease and two-dimensional echo showed pulmonary hypertension. Our patient followed both the Alarcon-Segovia's criteria and Kasukawa diagnostic criteria for mixed connective tissue disease (MCTD).
Conclusion: Pulmonary hypertension presents late in the illness when other clinical signs are easily recognizable and should be treated aggressively as most deaths in mixed connective tissue disorders are due to heart failure caused by pulmonary arterial hypertension.

Keywords: Mixed connective tissue disorder (MCTD), Raynaud's phenomenon, Sclerodactyly, Anti-U1RNP antibody, Scleroderma


[HTML Full Text]   [PDF Full Text]

Author Contributions
Rishi Katewa – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jakhar R.S. – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Barala G.L. – Substantial contributions to conception and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2014 Rishi Katewa et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



  Home line About IJCRI line Aim and Scope line Sections line Open Access line Archives
Apply as Editor line Apply as Reviewer line Submit Reviews - Editors line Submit Reviews - Reviewers
Instructions for Authors line Templates to Use line Copyright Form line Author Checklist
Online Submission line Email Submission line Submit Revision line Submit All Forms line Submit Page Proofs
Terms of Service line Privacy policy line Disclaimer line FAQ line Contact: Journal line Contact: Edorium Journals line Site Map
 
  Copyright © 2017. Edorium. All rights reserved.