International Journal of Case Reports and Images - IJCRI - Case Reports, Case Series, Case in Images, Clinical Images

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Case Report
 
Primary paediatric TH1immunodeficiency with BCG-osis
Sitaram Mohapatra1, Sudha Sethy1, Pranati Mohanty1, Ashoka Mohapatra2, Sarita Pradhan1
1Department of Pathology, SCB Medical College, Cuttack, Odisha, India.
2Department of Microbiology, SCB Medical College, Cuttack, Odisha, India.

doi:10.5348/ijcri-2012-05-123-CR-8

Address correspondence to:
Dr. Sitaram Mahapatra
Associate Professor, Department of Pathology
S.C.B. Medical College, Cuttack-753007
Odisha
India
Email: drsudhasethy@gmail.com

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How to cite this article:
Mohapatra S, Sethy S, Mohanty P, Mohapatra A, Pradhan S. Primary paediatric TH1 immunodeficiency with BCG-osis. International Journal of Case Reports and Images 2012;3(5):36–40.


Abstract
Introduction: In tuberculosis (TB) endemic regions BCG vaccine is administered at birth in an effort to protect against neonatal tuberculous meningitis. However, this live vaccine facilitates overwhelming systemic infections by otherwise innocuous organisms in infants with cellular primary immunodeficiencies .
Case Report: Our case is a seven month old infant who developed abscess at BCG vaccination site followed by disseminated BCG-osis and was diagnosed to have TH1 immunodeficiency.
Conclusion: Dissemination following BCG vaccination warrants prompt investigation to diagnose primary immunodeficiency disorders in HIV seronegative individuals.

Key Words: BCG-itis, BCG-osis, NTM, Immunodeficiency

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Author Contributions:
Sitaram Mohapatra - Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sudha Sethy - Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Pranati Mohanty - Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ashoka Mohapatra - Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sarita Pradhan - Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
Authors declare no conflict of interest.
Copyright:
© Sitaram Mohapatra et al. 2012; This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)



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