International Journal of Case Reports and Images - IJCRI - Case Reports, Case Series, Case in Images, Clinical Images

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Case Report
 
Primary extranodal marginal zone B-cell lymphoma of hard palate: A case report
Arpan K Shah1, Mahesh H Gabhane2, Meena M Kulkarni3
1Senior lecturer, Department of oral Pathology & Microbiology, MP Dental College & Hospital, Vadodara, Gujarat, India.
2Senior lecturer, Department of oral Pathology & Microbiology, SMBT Dental College & Hospital, Sangamner, Maharashtra, India.
3Professor & Head, Department of Oral Pathology & Microbiology, Rural Dental College & Hospital, Loni, Maharashtra, India.

doi:10.5348/ijcri-2012-05-119-CR-4

Address correspondence to:
Arpan K Shah
A-48/ Nilkanth Park
Tilakwada bypass road, Dabhoi
Gujarat
India - 391110
Phone: +919898932532
Email: drarpan_shah@rediffmail.com

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How to cite this article:
Shah AK, Gabhane MH, Kulkarni MM. Primary extranodal marginal zone B-cell lymphoma of hard palate: A case report. International Journal of Case Reports and Images 2012;3(5):21–24.


Abstract
Introduction: MALT (mucosa associated lymphoid tissue) lymphomas comprise a heterogeneous group, originally thought to be derived from the marginal zone B-cells that are found surrounding B-cell follicles and within the adjacent lymphoepithelium. They arise most commonly in extranodal organs such as the stomach, major salivary glands and thyroid. Thus, they can be precisely described as extranodal marginal zone B-cell lymphomas (ENMZL). Here, we report a case of MALT lymphoma arising in the palatal minor salivary glands.
Case Report: A 55-year-old woman presented with two years history of a left posterior palatal mass. Clinical investigations of the case included computed tomography (CT) scan for the assessment of bone destruction and possible intra-maxillary extension. Histopathological features and immunohistochemistry findings were consistent with the diagnosis of extranodal marginal zone B-cell lymphoma of MALT type. The lesion was treated by complete surgical excision and followed for two years.
Conclusion: Even though oral localization of ENMZL is rare, it should be included in the differential diagnosis of benign-appearing swellings of oral cavity.

Key Words: Extranodal, Histopathology, Lymphoma, MALT, Palate

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Author Contributions:
Arpan K Shah - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Mahesh H Gabhane - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Meena M Kulkarni - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
Authors declare no conflict of interest.
Copyright:
© Arpan K Shah et al. 2012; This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)



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