International Journal of Case Reports and Images - IJCRI - Case Reports, Case Series, Case in Images, Clinical Images

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CASE REPORT
 
A case report of typhoid fever masquerading as acute typhoid glomerulonephritis
B M Yashodhara1, Uduman Ali Mohamed Yousuf2
1Associate Professor, Department of Medicine, Melaka Manipal Medical College, Melaka, Malaysia.
2Professor, Department of Medicine, Melaka Manipal Medical College, Melaka, Malaysia.

doi:10.5348/ijcri-2011-03-21-CR-1

Address correspondence to:
Dr. BM Yashodhara
Associate Professor
Department of Medicine
Melaka Manipal Medical College- 75150
Melaka Malaysia
Phone: 006-0176948029
Email: bmyashodhara@gmail.com

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How to cite this article:
Yashodhara BM, Yousuf UAM. A case report of typhoid fever masquerading as acute typhoid glomerulonephritis. International Journal of Case Reports and Images 2011;2(3):1-4.


Abstract
Introduction: Typhoid fever is a common infectious disease worldwide, especially in developing countries. Typhoid fever presenting as nephritis is rare. The common renal complications of typhoid fever are pyelonephritis and cystitis. Patients with typhoid glomerulonephritis may present with acute renal failure, hypertensive encephalopathy or nephritic syndrome. Presence of typhoid nephritis increases mortality to 20-30% in untreated typhoid fever.
Case Report: We report a case of a 29-year-old patient in this case report who presented with fever, hypertension, pedal oedema, and hematuria. Widal was positive in high titres and blood culture grew Salmonella typhi. His fever, hypertension and oedema resolved on treatment for the infection.
Conclusion: Typhoid fever presenting as typhoid glomerulonephritis is a rare occurrence and has to be considered in patients in endemic areas, presenting with nephritis and concomitant fever. High index of suspicion, prompt early diagnosis is beneficial, in preventing morbidity and mortality related to with Salmonella typhi infection.

Key Words: Typhoid glomerulonephritis, Typhoid fever, Nephritis, Acute renal failure

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Author Contributions:
Yashodhara BM - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Uduman Ali Mohamed Yousuf - Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
The author(s) declare no conflict of interests
Copyright:
© BM Yashodhara et. al. 2010; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)



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